清凉活化散载药护膝对膝骨关节炎急性发作的临床疗效与护理

Clinical efficacy of Qingliang Huohua powder-loading kneepad on acute attack of knee osteoarthritis and its nursing

目的探讨清凉活化散载药护膝对膝骨关节炎急性发作的临床疗效和护理要点。方法选取膝骨关节炎急性期患者348例,将其随机分为三组,即弹力绷带组、扶他林组与载药护膝组各116例。前两组为对照组。扶他林组遵医嘱予扶他林乳膏外涂治疗;弹力绷带组用本院院内制剂清凉活化散外敷,以弹力绷带固定;载药护膝组给予本院研制的载药护膝承载清凉活化散外敷。三组治疗中均辅以适宜的护理措施。观察疼痛、肿胀、活动度、依从率、不适感发生率及满意率,进行疗效评价。比较载药护膝组与弹力绷带组、扶他林组各项指标差异。结果载药护膝组疼痛积分与弹力绑带组比较,P<0.05。载药护膝组肿胀积分与扶他林组比较,P<0.01。载药护膝组活动度与扶他林组比较,P<0.01,载药护膝组活动度与弹力绷带组比较,P<0.05。载药护膝组总有效率与扶他林组比较,P<0.01。载药护膝组不适感发生率与弹力绷带组比较,P<0.05。载药护膝组满意率与弹力绷带组比较,P<0.05。依从率三组无差异。结论与弹力绷带组、扶他林组比较,载药护膝组在症状改善、疗效、不适感发生率、满意率或与其相当,或明显提高,基本完成改进预期,值得临床推广应用。

Objective To explore the the clinical efficacy and nursing essentials of Qingliang Huohua powder-loading kneepad on acute attack of knee osteoarthritis. Methods A total of 348 patients with acute knee osteoarthritis were se- lected, and were randomly divided into three groups： the elastic bandage group, Fuatlin group and drug-loading kneepad group, with 116 patients in each group. The first two groups were the control groups. Fuatlin group was pre- scribed with external application of Fuatlin cream; elastic bandage group was given the external application of Qingliang Huohua powder prepared by our hospital, and fixed by the elastic bandage; drug-loading kneepad group was given the external application of Qingliang Huohua powder-loading kneepad prepared by our hospital. The three groups were supplemented by appropriate nursing care measures during the treatment. The pain, swelling, mobility, compliance rate, the incidence rate of discomfort and satisfaction rate were observed, and the efficacy was evaluated. The differ- ences of the indices between the drug-loading kneepad group, the elastic bandage group and the Fuatlin group were compared. Results The difference of pain score between the drug-loading kneepad group and the elastic bandage group was significant （P〈0.05）. The difference of swelling score between the drug-loading kneepad group and Fuatlin group was significant （P〈0.01）. The difference of mobility between the drug-loading kneepad group and Fuatlin group was sig- nificant （P〈0.01）, and the difference of mobility between the drug-loading kneepad group and the elastic bandage group was significant （P〈0.05）. The difference of the total effective rate between the drug-loading group and the Fuatlin group was significant （P〈0.01）. The difference of the incidence of discomfort between the drug-loading kneepad group and the elastic bandage group was significant（P〈0.05）. The difference of the satisfaction rate between the drug-loading kneepad group and the elastic bandage group was significant（P〈0.05）. There was no difference in the compliance rate among the three groups. Conclusion Compared with the elastic bandage group and the Fuatlin group, the improvement of symp- toms, curative effect and the incidence rate of discomfort, and the satisfaction rate in the drug-loading kneepad group is equivalent, or significantly better, and the improvement expectation is basically completed, which is worthy of clini- cal promotion and application.