腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征后妊娠的临床观察

Clinical observation of laparoscopic ovarian perforation combined with Diane-35 in the treatment of pregnancy after polycystic ovary syndrome

目的观察分析腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征后的妊娠情况。方法选取2015年1~12月于我院就诊的多囊卵巢综合征患者130例,采用随机数字法将患者均分为联合组(n=65)与药物组(n=65),联合组患者给予腹腔镜卵巢打孔联合达英-35治疗,药物组患者仅给予达英-35治疗,对比两组患者的治疗效果。结果两组患者治疗前的血清性激素水平差异无统计学意义(P>0.05);两组患者治疗后的T、LH水平低于治疗前(P<0.05),且联合组患者治疗后的T、LH水平低于药物组(P<0.05);联合组患者的妊娠率、足月分娩率显著高于对照组(P<0.05)。结论腹腔镜卵巢打孔配合达英-35治疗多囊卵巢综合征的临床疗效良好,可有效降低T、LH水平,治疗后患者的妊娠率及足月分娩率较高,是治疗多囊卵巢综合征后妊娠的有效方法之一。

Objective To observe and analyze the laparoscopic ovarian puncture combined with Diane-35 in the treatment of pregnancy after polycystic ovary syndrome. Methods A total of 130 patients with polycystic ovary syndrome treated in our hospital from January tO December 2015 were chosen and randomly divided into the combined group（n= 65） and the drug group（n=65） according to the digital random method. The patients in the combined group were treated with laparoscopic ovarian perforation combined with Diane-35 treatment. The patients in the drug group were treated with Diane-35 only. And the therapeutic effect was compared between the two groups. Results There was no significant difference in serum sex hormone level between the two groups before treatment（P〉0.05）. The levels of T and LH in the two groups after treatment were lower than those before treatment, and the levels of T and LH in the combined group were lower than those in drug group（P〈O.05）. The pregnancy rate and full-term delivery rate of the combined group were significantly higher than those of the drug group（P〈0.05）. Conclusion Laparoscopic ovarian perforation combined with Diane-35 has a good clinical effect in the treatment of polycystic ovary syndrome, which can effectively reduce the level of T and LH. The pregnancy rate and full-term delivery rate of patients after treatment are higher. The combined treat- ment is one of the effective treatment methods for pregnancy after polycystic ovary syndrome.