血清C肽与糖化血红蛋白联合检测在糖尿病患者临床诊断中的作用

The Effect of Serum C Peptide Combined Glycosylated Hemoglobin in the Diagnosis of Patients With Diabetes Mellitus

目的分析血清C肽和糖化血红蛋白联合检测在糖尿病患者诊断中的应用。方法将46例2型糖尿病患者与42例健康体检者分别作为观察组、对照组,检测两组血清C肽与糖化血红蛋白水平。结果观察组糖化血红蛋白高于对照组,血清C肽低于对照组(P<0.05);两指标联合诊断时,对2型糖尿病的诊断灵敏度、特异度、准确度最高。结论血清C肽和糖化血红蛋白联合检测可提高糖尿病诊断准确性。

Objective To analyze the clinical application of combined detection of serum C peptide and HbAlc in patients with diabetes. Methods 46 cases of patients with type 2 diabetes and 42 healthy subjects were selected into observation group and control group, serum C peptide and HbAlc levels of two groups were tested. Results The glycosylated hemoglobin in the observation group was significantly higher, the serum C peptide was significantly lower than the control group （P 〈 0.05）, the sensitivity, specificity, accuracy was highest with the combination of two diagnostic parameters in diagnosis of type 2 diabetes. Conclusion The combined detection of serum C peptide and HbAlc can improve the accuracy of diagnosis of diabetes.