七氟醚在开颅血肿清除术中维持麻醉的临床效果观察

Clinical Observation on Sevoflurane in Maintaining Anesthesia During Craniotomy and Hematoma Evacuation

目的对七氟醚在开颅血肿清除术中维持麻醉的临床效果进行观察。方法选取2014年2月—2016年12月收治的30例开颅血肿清除术的患者,将其分为对照组与观察组,对照组予以瑞芬太尼、丙泊酚静脉持续泵注,观察组予以瑞芬太尼维持麻醉,七氟醚吸入,并观察两组患者各时段的收缩压(SBP)、舒张压(DBP)、脉搏氧饱和度(SPO_2)、心率(HR)及血管活性药物的使用情况。结果观察组开颅血肿清除术患者于手术开始时、手术结束后的SBP、DBP、HR,与对照组对比,差异具有统计学意义(P<0.05);且血管活性药物去氧肾上腺素、乌拉地尔和阿托品用量均少于对照组,P<0.05。结论对于开颅血肿清除术中维持麻醉的患者,予以七氟醚吸入的效果显著。

Objective To observe the clinical effect of sevoflurane in maintaining anesthesia in craniotomy and hematoma evacuation. Methods Thirty patients with craniotomy who underwent craniotomy and hematoma evacuation from February 2014 to December 2016 were divided into control group and observation group. The control group was treated with intravenous continuous pump of remifentanil and propofol, the study was given maintaining anesthesia of remifentanil and inhalation of sevoflurane, systolic blood pressure （SBP）, diastolic blood pressure （DBP）, pulse oxygen saturation （SPO2）, heart rate （HR） were measured in the two groups of patients, the use of vasoactive drugs was analysed. Results The SBP, DBP and HR of the patients in the observation group were significantly lower than those in the control group at the beginning of the operation （P〈0.05）, and the dosage of vasoactive drugs, phenylephrine, urapidil and atropine were less than those in the control group （P〈0.05）. Conclusion For patients undergoing craniotomy and hematoma evacuation, the effect of sevoflurane inhalation during maintaining anesthesia is remarkable.