右美托咪定对扁桃腺切除术患儿七氟醚复合麻醉苏醒期噪动的影响

Efficacy of Dexmedetomidine on Emergence Agitation During the Recovery Period of Sevoflurane Anesthesia in Pediatric Undergoing Tonsillectomy

目的研究右美托咪定对扁桃腺切除术患儿七氟醚复合麻醉苏醒期躁动的影响。方法选取2015年1月—2017年1月我院拟在全麻气管插管下行扁桃体及腺样体切除手术的患儿80例,将其随机分为观察组和对照组,每组各40例。观察组插入气管导管后,输注右美托咪定0.2μg/(kg·h),对照组则输注等剂量的生理盐水,比较两组麻醉苏醒期躁动的影响。结果观察组的PAED评分低于对照组,观察组的躁动发生率、不良反应发生率均低于对照组,观察组的PACU停留时间低于对照组,差异均有统计学意义(P<0.05)。结论使用右美托咪定有助于减少患儿苏醒期躁动,帮助患儿平稳度过麻醉苏醒期,并减少术后的不良反应。

Objective To study the effect of dexmedetomidine on emergence agitation during the recovery period of sevoflurane anesthesia in pediatric undergoing tonsillectomy. Methods 80 cases of tonsillectomy pediatric treated with sevoflurane anesthesia admitted in our hospital from January 2015 to January 2017 were divided into control group and observation group by method of random sampling, 40 cases in each group, the observation group was administered dexmedetomidine treatment 0.2 pg/（kg＇h）, and the control group was administered same dose of normal saline treatment, the efficacy of emergence agitation during recovery period of two groups were observed and compared. Results In observation group, the PAED score, emergence agitation rate, adverse reaction rate and PACU staying period were lower than these in control group, the difference was statistically significant （P〈0.05）. Conclusion The use of dexmedetomidine can reduce emergence agitation in pediatric, and help pediatric get through the anesthesia recovery period, and reduce postoperative adverse reactions.