不同麻醉方式对腹部手术患者循环状态及T淋巴细胞亚群的影响

Influence of different anesthesia methods on the circulation state and T lymphocyte subsets of patients with abdominal operation

目的探讨不同麻醉方式对腹部手术患者循环状态及T淋巴细胞亚群的影响。方法选取120例腹部手术患者,将其分为A组(全麻组)和B组(硬膜外复合全麻组),比较2组患者不同时间点的血流动力学指标、心排量指标及外周血T淋巴细胞亚群指标。结果术中5 min、术中30 min及术后5 min,B组的血流动力学指标均显著低于A组(P<0.05),术后1 d及3 d时B组的外周血T淋巴细胞亚群指标均显著好于A组(P<0.05)。结论硬膜外复合全麻对腹部手术患者循环状态及T淋巴细胞亚群的影响较小,更适用于腹部手术患者。

Objective To explore the influence of different anesthesia methods on the circulation state and T lymphocyte subsets of patients with abdominal operation. Methods A total of 120 patients with abdominal operation were divided into group A （general anesthesia group）and group B （epidural combined anesthesia group）. The hemodynamic indexes, cardiac output indexes and peripheral blood T lymphocyte subsets at different time points were analyzed and compared between two groups. Results The hemodynamic indexes at 5 rain and 30 min during the operation and 5 rain after the operation in the group B were significantly lower than those iu the group A （P 〈 0.05）, and the peripheral blood T lymphocyte subsets of group B at first and third day after the operation were significantly better than group A （ P 〈 0.05 ）. Conclusion The effect of epidural general anesthesia on the eireulatory status and T lymphoeyte subsets in patients with abdominal operation is less, which is more suitable for patients with abdominal surgery.