鱼油脂肪乳在重症急性胰腺炎病人中的研究进展

The research development of oil fat emulsion in severe acute pancreatitis

重症急性胰腺炎(SAP)的患病率呈逐年上升,病死率高,严重威胁着病人的生命。近年来,免疫营养在SAP的治疗中成为研究热点,其中免疫营养中的鱼油脂肪乳作为一种新型的脂肪乳剂,既能为机体提供营养、调节代谢,又能抑制炎性反应、降低氧化应激、调节免疫和信号转导、保护各重要器官,能有效地抑制全身性炎症反应综合征(SIRS)向多器官功能障碍综合征(MODS)发展,改善病人的预后。

The incidence of severe acute pancreatitis（SAP） is increasing year by year, and the mortality is high, which poses a great threat to the life of patients. In recent years, the immune nutrition therapy has become the focus in the treatment of SAP, among which, fish oil lipid emulsion as a novel type of fat emulsion, has the multi-effects of anti-inflammatory, anti-oxidative, immunomodulatory, promoting signal transduction and protecting organ function apart from providing nutrition and regulating metabolism. It can prevent the deterioration of the whole body from systemic inflammatory response syndrome （SIRS） to multiple organ dysfunction syndrome （MODS） and ultimately improve the prognosis of patients.