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软骨和软骨下骨的生物力学相互作用对骨关节炎影响的研究进展 被引量:7

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摘要 骨关节炎属中医"痹证"范畴,其主要特征表现为关节软骨退化。但目前研究发现,骨关节炎的发生和发展并不只是一个简单的软骨磨损过程,而是发生在整个关节各组织间的复杂的渐进的化学、生物和机械的变化,特别是软骨和软骨下骨之间的生物力学相互作用对骨关节炎的发生和发展起重要作用。本文从软骨和软骨下骨的正常生物力学特征和作用、骨关节炎发展过程中软骨和软骨下骨的变化及其影响、软骨和软骨下骨的生物力学相互作用对骨关节炎预防和治疗的启发3个方面对相关研究进展进行了综述。
出处 《中医正骨》 2017年第5期23-26,30,共5页 The Journal of Traditional Chinese Orthopedics and Traumatology
基金 上海市自然科学基金项目(15ZR1441000) 上海市浦东新区卫生和计化生育委员会卫生科技项目(PW2014A-20) 上海市浦东新区卫生系统重点学科建设项目(PWZx2014-17 PDWZ2014-12)
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  • 1GAO J, DENNIS J E, SOLCHAGA L A, et al. Tissue-engi- neered fabrication of an osteochondral composite graft using rat bone marrow-derived mesenchymal stem cells[J]. Tissue Engineering, 2001,7(4) :363-371.
  • 2SCHAEFER D, MARTIN I, SHASTRI P, et al. In vitro Generation of osteochondral composites [-J. Biomaterials, 2000,21(24) :2599-2606.
  • 3ALHADLAQ A, MAO J J. Tissue-engineered osteochondral constructs in the shape of an articular condyie[J]. The Journal of Bone and Joint Surgery. American Volume, 2005,87 (5) : 936-944.
  • 4ALHADLAQ A, MAO J J. Tissue-engineered neogenesis of human-shaped mandibular condyle from rat mesenchymal stem cells[J]. Journal of Dental Research, 2003,82(12) :951- 956.
  • 5CHANG C H, LIN F H, LIN C C, et al. Cartilage tissue engi neering on the surface of a novel gelatin calcium-phosphate bi- phasic scaffold in a double-chamber bioreactor[J]. Journal of Biomedical Materials Research Part B--Applied Biomaterials, 2004,71(2) :313-321.
  • 6ESTES B T, GIMBLE J M, GUILAK F. Mechanical signals as regulators of stem cell fate[J]. Current Topics in Develop mental Biology, 2004,60(1) :91-126.
  • 7WALDMAN S D, SPITERI C G, GRYNPAS M D, et al. Long term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro[J]. Journal of Orthopae- dic Research= Official Publication of the Orthopaedic Research Society, 2003,21(4) =590-596.
  • 8SCHLEICHER I, LIPS K S, SOMMER U, et al. Biphasic scaffolds for repair of deep osteochondral defects in a sheep model[J]. The Journal of Surgical Research, 2013,183 (1) : 184-192.
  • 9BERNSTEIN A, NIEMEYER P, SALZMANN G, et al. Os- teochondral tissue regeneration using a bilayered composite hy drogel with modulating dual growth factor release kinetics in a rabbit model[J]. Acta Biomaterialia, 2013,9(12) = 7490-7505.
  • 10MAYR H O, KLEHM J, SCHWAN S, et al. Microporous Calcium phosphate ceramics as tissue engineering scaffolds for the repair of osteochondral defects: biomechanical results[J]. Acta Biomaterialia, 2013,9(1) :4845- 4855.

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