西咪替丁与干扰素联合微量元素锌在小儿轮状病毒感染性腹泻中的应用疗效分析

Application curative effect analysis of cimetidine associated with interferon trace element Zn in infantile rotavirus infectious diarrhea

目的分析西咪替丁与干扰素联合微量元素锌在小儿轮状病毒感染性腹泻中的应用疗效。方法收集我院自2015年11月~2016年12月收治的67例轮状病毒感染性腹泻患儿,分为对照组(实施西咪替丁与干扰素治疗)与治疗组(实施西咪替丁与干扰素联合微量元素锌治疗),对两组患儿疗效进行观察。结果治疗组脱水、大便以及体温等的恢复时间均分别明显短于对照组(P<0.05);治疗组治疗总有效率为97.14%,明显高于对照组的71.88%(P<0.05);两组不良反应对比未见明显差异(P>0.05)。结论针对轮状病毒感染性腹泻患儿,对其实施西咪替丁与干扰素联合微量元素锌治疗,能够快速缓解其症状,具有疗效理想,安全性高的优势,具有较高的推广价值。

Objective To curative effect analyze cimetidine and interferon combination of trace element zn in pediatric infectious diarrhea rotavirus. Methods 67 cases of children with infectious diarrhea rotavirus in our hospital from November 2015 to December 2016 were selected and divided into control group （implementation of cimetidine and interferon therapy） and treatment group （the implementation of cimetidine associated with interferon therapy trace element zine）. The curative effect of two groups were observed. Results The dehydration, stool and the recovery of body temperature and time of treatment group were significantly shorter than those of control group （P 〈 0.05）. The total effective rate of treatment group was 97.14%, which was significantly higher than that of control group with 71.88% （P 〈 0.05）. There was no significant difference between the two groups on adverse reactions （P 〉 0.05）. Conclusion In children with infectious diarrhea rotavirus, imposed cimetidine and interferon combined therapy with trace elements zinc can quickly relieve symptoms. Its curative effect is ideal The advantages of high safety is of high popularization value.