胃癌病人术后限制性输液对近期临床结局的影响

Gastric cancer patients with postoperative restrictive transfusion in the recent clinical outcomes

目的观察胃癌病人术后限制性输液对近期临床结局的影响。方法将80例胃癌病人按照随机表格法分为常规输液的对照组40例和限制性输液的限制组40例。动态监测比较两组病人术后连续4天输液量、术后发热时间、术后恢复肛门排气排便时间、并发症发生例数(切口感染,切口裂开,吻合口瘘,心律失常,肺部感染,呼吸衰竭等)、术后住院天数及白细胞、C反应蛋白(CRP)、血红蛋白、谷草转氨酶(AST)、谷丙转氨酶(ALT)、葡萄糖,尿素氮(BUN)、血肌酐(Cr)、BNP等。结果限制组病人术后第1和第3天白细胞明显低于对照组;术后第1、3天和第7天CRP明显低于对照组(P<0.05);限制组病人术后发热时间、肛门排气排便时间、住院天数明显少于对照组(P<0.05),术后并发症的发生减少。结论胃癌病人术后限制性输液可加速患者康复,降低术后并发症发生率。

Objective Is to observe the postoperative gastric cancer patients restrictive transfusion in the recent clinical outcomes. Methods Eighty cases of gastric cancer patients are divided into conventional infusion in the control group 40 cases and the limitation of the restrictive infusion group 40 cases. Dynamic monitoring to compare two groups of patients with postoperative transfusion volume for 4 days, the time of postoperative fever, post-operation anus exhaust time defecate, complications of cases, infection of incision, incision dehiscence, anastomotic fistula, arrhythmia, pulmonary infection, respiratory failure, etc.）, postoperative hospitalization days and white blood cells, c-reactive protein （CRP）, hemoglobin, aspertate aminotransferase （AST）, alanine aminotransferase （ALT）, glucose, urea nitrogen （BUN）, serum creatinine （Cr）, the BNP, etc. Results The patients postoperative days 1 and 3 white blood cells limit group was obviously lower than the control group; Postoperative days 1, 3 and 7 CRP significantly lower than the control group （P〈 0.05）; limited group of patients with postoperative fever time, anal exhaust time, hospitalization days defecate significantly less than the control group （P〈0.05）, less postoperative complications happened. Conclusion The gastric cancer patients postoperative patients with restrictive transfusion can accelerate recovery, reduce the incidence of postoperative complications.