苯磺酸左旋氨氯地平联合镇肝熄风汤对阴虚阳亢型老年高血压患者的疗效分析

Analysis of the effectiveness of levamlodipine besylate combined with Zhenganxifeng decoction on elderly patients with hypertension of type deficiency of Yin and excess of Yang

目的分析苯磺酸左旋氨氯地平联合镇肝熄风汤中西医结合对阴虚阳亢型老年高血压患者的疗效。方法将我院2014-06—2016-09收治的120例阴虚阳亢型高血压的老年患者为研究对象,随机分为观察组和对照组各60例。对照组仅采用苯磺酸左旋氨氯地平治疗,观察组采用苯磺酸左旋氨氯地平联合镇肝熄风汤进行中西医结合治疗。对比2组治疗前后肝功能、肾功能、血脂、血压和心电图等指标。结果治疗后2组血压均明显降低,且观察组降幅明显优于对照组(P<0.05);观察组症状积分明显优于对照组(P<0.05);治疗后观察组血脂水平低于治疗前,但2组血脂水平比较差异无统计学意义(P>0.05)。结论采用苯磺酸左旋氨氯地平联合镇肝熄风汤治疗阴虚阳亢型老年高血压的降压效果明显优于单纯西药治疗,镇肝熄风汤可有效调节老年高血压患者的血脂水平,具有较好的临床疗效,且安全性较高。

Objective To analyze the effect of levamlodipine besylate combined with Zhenganxifeng decoction on elderly patients with hypertension of type deficiency of Yin and excess of Yang.Methods Totally 120 elderly patients suffering from hypertension of type deficiency of Yin and excess of Yang in our hospital between June 2014 and September 2016 were collected and were divided into two groups randomly：observation group and control group （60 cases in each group）.Patients in the control group were treated with levamlodipine besylate,while the patients in the observation group were treated with levamlodipine besylate combined with Zhenganxifeng decoction.Changes in parameters of liver function,renal function,blood lipid,blood pressure and electrocardiogram were assessed and compared between the two groups.Results Compared with pre-treatment,the blood pressure was significantly reduced in both groups,and the changes in observation groups were significantly larger than those of control group （P〈0.05）.The symptom scores in observation group were significantly better than those of control group （P〈0.05）.After treatment,the blood lipid of observation group was lower than that before treatment,but there was no significant difference （P〉0.05）.Conclusion The use of levamlodipine besylate combined with Zhenganxifeng decoction for elderly patients with hypertension of type deficiency of Yin and excess of Yang is superior to the use of levamlodipine besylate alone.Zhenganxifeng decoction can effectively regulate the blood liquid of the elderly patients with hypertension,with a good clinical safety and efficiency.