人参鹿茸保健品缓解体力疲劳作用研究

Study on Alleviating Physical Fatigue of Health-care Products Ginseng and Pilose Antler

[目的]研究以人参、鹿茸、蝙蝠蛾拟青霉菌丝粉为主材料的保健食品的缓解体力疲劳作用。[方法]ICR雄性小鼠160只,随机分为4组,设置低、中、高3个剂量[0.17、0.33、1.00 g/(kg·d)]组和空白对照组,连续灌胃30 d。小鼠经负重游泳后,观察负重游泳时间,检测血清尿素、肝糖原、血乳酸含量等几种与疲劳作用相关的生物化学指标。[结果]各试验组与空白对照组比较,不同剂量组小鼠负重游泳时间明显延长,高剂量组作用显著(P<0.05);运动小鼠血清尿素及血乳酸曲线下面积明显降低,高剂量组作用显著(P<0.05);各剂量组肝糖原储备与空白对照组比较均无显著性差异(P>0.05)。[结论]这种以人参、鹿茸、蝙蝠蛾拟青霉菌丝粉为主材料的保健食品具有缓解体力疲劳作用,这为开发人参功能性食品提供了理论依据。

[ Objective ] The research aimed to study the health food （ginseng, pilose antler, paecilomyces hepiali mycelium as the main material ） to relieve physical fatigue. [ Method] 160 mice were allocated randomly into 4 groups. High, medium and low three dose groups were set, blank control group was treated with distilled water, the samples were administered through the mice by mouth, once a day, 30 consecutive days. Then fatigue-related biochemical indicators were analyzed, including the loaded-swimming time, serum urea, hepatic glycogen and blood lactic acid after exercise. [ Result] Compared with the blank control group, the time of weight-bearing swimming was significantly pro- longed in different dose groups, and the effect of high dose group was significant （ P 〈 0.05 ）. The area under the curve of serum urea and blood lactate in exercise mice was significantly decreased, and the effect of high dose group was significant （P 〈 0.05 ）. There was no significant difference in hepatic glycogen content between the experimental groups and the control groups （ P 〉 0.05 ）. [ Conclusion ] This kind of health food with ginseng, pilose antler and paecilomyces hepiali mycelium has the effect of relieving physical fatigue, which provides the theoretical basis for the development of ginseng functional food.