MAPK在寄生虫领域的研究进展

Advances in parasitology research on the role of the MAPK signal transduction pathway

MPAK在寄生虫的生长、增殖、入侵以及感染机体相互作用中发挥了重要的调节作用,通过研究了解各类寄生虫自身以及寄生虫与宿主之间的信号转导关系,从MAPK在寄生虫生命活动中的功能意义、在宿主体内的检验检测、提取基因作药物靶点、抗原性蛋白作疫苗候选分子以及应用MAPK抑制剂调控寄生虫生理活动等方面对认识和处理寄生虫领域问题取得新的启示。

Mitogen-activated protein kinase （MAPK） plays an important role in parasite growth, proliferation, and invasion and an important role in interaction between the parasite and host. Research will provide an understanding of signa-ling between a parasite and host. Topics such as the significance of MAPK to a parasite＇s vital functions, detection of MAPK in a host, identification of certain genes to target with drugs, using antigenic proteins as molecules for potential vaccines, and using MAPK inhibitors to regulate and control a parasite＇s physiological activity provide new insights to un- derstand and deal with issues in parasitology.