消肿止痛汤治疗胫腓骨骨折早期肿胀临床疗效观察

Clinical Observation on Effects of Xiaozhongzhitong Decoction Treating Early Swelling of Tibiofibula Fractures

目的:观察消肿止痛汤治疗胫腓骨骨折早期肢体肿胀的临床疗效。方法:将64例胫腓骨骨折后肢体肿胀患者随机分为治疗组和对照组,每组32例。治疗组口服中药消肿止痛汤,1剂/d,水煎分2次服用;对照组静滴20%甘露醇250 ml/次,30 min滴完,间隔8 h重复1次,观察两组肢体消肿时间、疼痛减轻情况、肿胀减轻程度、临床疗效及药物不良反应。结果:治疗组、对照组肢体肿胀消退时间分别为(6.07±0.92)d、(6.18±1.01)d,总有效率分别为93.8%、84.4%,两组治疗3 d后VSA疼痛评分比较,差异有统计学意义(P<0.05)。结论:消肿止痛汤治疗胫腓骨骨折后肢体肿胀有良好的消肿作用,中药消肿止痛汤疗效优势明显。

Objective： To observe curative effect of Xiaozhongzhitong decoction treating early swelling of tibiofibula fractures. Methods： 64 Patients with early swelling of tibiofibula fractures were divided into treatment group and comparative group, 32 patients in each group. The treatment group were given Xiaozhongzhitong decoction twice a day, the comparative group were given 20% mannitol 250 ml within 30 min, once 8 hours. Time of limb swelling, decrease of pain, clinical observation and drug adverse reaction were compared as main indicators. Results： Time of limb swelling subsided in the treatment group and comparative group were （6.07± 0.92）, （6.18± 1.01） d respectively, the efficient of the two groups were 93.7%, 90.6%, after treatment, the VSA score of the two groups was statistically significant （P 〈0.05）. Conclusions： Xiaozhongzhitong decoction treating early swelling of tibiofibula fractures is eutherapeutic, which is recommendable for clinical application.