舒芬太尼在儿童手术的术后镇痛效果及安全性

Application of sufentanil in pediatric surgery and postoperative analgesia

目的分析析舒芬太尼在儿童手术的术后镇痛效果及安全性。方法选取西宁市第三人民医院儿科2013年7月~2015年1月收治的80例小儿手术患者作为研究对象,采用单双号法分为对照组和观察组,每组40例。对照组给予瑞芬太尼,观察组给予舒芬太尼,并记录患儿进入手术室后5 min基础值、诱导后、气管插管后、插管后30 min及拔管后5 min各时点的平均动脉压（mean arterial pressure,MAP）和心率（heart rate,HR）。同时记录术后5 min、15 min和30 min的镇静评分。结果观察组在术后T_4、T_5、T_6各时段镇痛评分均明显高于对照组（P〈0.05）;观察组在T_0、T_1、T_2、T_3各时期MAP和HR与对照组比较,差异无统计学意义,但观察组T_4时MAP明显高于对照组（P〈0.05）;而观察组在T_4时HR明显低于对照组（P〈0.05）。结论舒芬太尼应用于小儿手术镇痛效果明显,且安全性较高。

Objective To investigate the safety and efficacy of sufentanil in pediatric surgery.Methods80 cases of pediatric surgery were prospectively selected pediatric methods in The Third People＇s Hospital of Xining from July 2013 to January 2015 as the research object, the patients were divided into two groups, control group and observation group, 40 cases in each group.The control group received remifentanil,observation group were given sufentanil, mean arterial pressure（MAP）and heart rate（HR）30min and 5min at each time point after extubation and 5min based value children after entering the operation room after induction were compared.The sedation scores of 5min, 15min and 30min after tracheal intubationwere recorded..ResultsThe pain scores in the observation grouppostoperative T4, T5, T6 each time were significantly higher than the control group （P〈0.05）;MAP and HRin the observation group at T0, T1, T2, T3 had no significant differencecompared with control group, MAP during T4 in the observation group was significantly higher than the control group （P〈0.05）;and HR in the observation group in the period of T4 was significantly lower than the control group （P〈0.05）.ConclusionThe application of sufentanil in pediatric surgery is effective and safe.