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OCT对玻璃体腔注射康柏西普治疗脉络膜新生血管的疗效观察

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摘要 目的观察光学相干断层扫描(OCT)在玻璃体腔注射康柏西普治疗脉络膜新生血管临床效果中的应用效果。方法选择2015年10月至2016年4月我院收治的30例脉络膜新生血管患者为研究对象,所有患者均给予玻璃体腔注射康柏西普治疗,治疗前后均接受视力检查、眼底荧光造影检查、OCT检查及6个月随访观察,评估本组患者治疗效果。结果治疗后,脉络膜新生血管患者黄斑中心凹视网膜神经上皮层厚度(255.6±74.2)μm,显著低于治疗前厚度(355.9±113.6)μm,差异有统计学意义(t=13.943,P<0.001)。治疗后,脉络膜新生血管患者黄斑中心凹3 mm位置的鼻侧、颞侧、上方、下方的平均视网膜神经上皮层厚度(288.3±52.4)μm,显著低于治疗前厚度(322.5±75.6)μm,差异有统计学意义(t=8.074,P<0.001)。治疗后,出现局部球结膜出血患者2例,无其他明显不良反应。结论 OCT检测在玻璃体腔注射康柏西普治疗脉络膜新生血管患者临床疗效判定中有着良好的应用价值,对收集患者黄斑区预后信息、评估患者治疗预后效果等均有积极效果。
作者 姜俊
出处 《齐齐哈尔医学院学报》 2017年第7期801-802,共2页 Journal of Qiqihar Medical University
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