期刊文献+

血清胆囊收缩素A受体水平对腹腔镜保胆取石术临床疗效的影响 被引量:7

下载PDF
导出
摘要 目的探讨血清胆囊收缩素A受体(CCKAR)水平对腹腔镜保胆取石术临床疗效的影响。方法选取2013年6月至2015年12月肝胆外科诊治的64例胆囊结石患者为研究对象,并采用腹腔镜保胆手术治疗,分别记录患者的手术时间、住院时间、术中出血量、肠蠕动恢复时间、胆漏、腹腔积液及切口感染等并发症的发生情况;采用酶联免疫吸附试验测定患者血清CCKAR的水平。结果以CCKAR中位测定值2.26ng/mL为界,将患者分为CCKAR高水平组(33例)和低CCKAR水平组(31例);两组患者年龄、性别、病程、结石平均内径、手术时间、住院时间和术中出血量比较差异均无统计学意义(P>0.05);但CCKAR高水平组的肠蠕动恢复时间明显低于CCKAR低水平组,差异有统计学意义(P<0.05);CCKAR低水平组的并发症发生率为25.81%,则明显高于CCKAR高水平组的6.06%,差异有统计学意义(P<0.05)。结论低水平CCKAR患者行腹腔镜保胆取石术后肠蠕动恢复时间长,且并发症发生风险高。
出处 《检验医学与临床》 CAS 2017年第11期1623-1625,共3页 Laboratory Medicine and Clinic
基金 重庆市卫生局医学科研计划项目(2010-2-445)
  • 相关文献

参考文献2

二级参考文献43

  • 1Xiong Ding, Chang-You Lu, Ying Mei, Chang-An Liu and Yu-Jun Shi Chongqing, China Department of Hepatobiliary Surgery, Second Clinical College, Chongqing Medical University, Chongqing 400010, China.Correlation between gene expression of CCK-A receptor and emptying dysfunction of the gallbladder in patients with gallstones and diabetes mellitus[J].Hepatobiliary & Pancreatic Diseases International,2005,4(2):295-298. 被引量:20
  • 2Bradford M M.A rapid and sensitive method for the quantitation of microgram quantities of protein ustilizing the principle of protein-dye bindingAnalytical Biochemistry,1976.
  • 3Wank SA.Cholecystokinin receptors,1995(01).
  • 4Lowenfels AB;Maisonnenve P;Boyle P.Epidemiology of gallbladder cancer,1999(46).
  • 5Allred DC;Harvey JM;Berardo M.Prognostic and predictive factors in breast cancer by immunohistochemical analysis,1998(02).
  • 6Randi G,Franceschi S,La Vecchia C.Gallbladder cancer worldwide: geographical distribution and risk factors. Int J Cancer . 2006
  • 7Goldin RD,Roa JC.Gallbladder cancer:a morphological and molecular update. Histopathology . 2009
  • 8Keun Hur,Mi Kyung Kwak,Hyuk-Joon Lee,Do Joong Park,Hyeon Kook Lee,Hye Seung Lee,Woo Ho Kim,Dov Michaeli,Han-Kwang Yang.Expression of gastrin and its receptor in human gastric cancer tissues[J]. Journal of Cancer Research and Clinical Oncology . 2006 (2)
  • 9Norikazu Sato,Kyoko Miyasaka,Shinji Suzuki,Setsuko Kanai,Minoru Ohta,Takako Kawanami,Yuki Yoshida,Soichi Takiguchi,Tetsuo Noda,Yutaka Takata,Akihiro Funakoshi.Lack of Cholecystokinin-A Receptor Enhanced Gallstone Formation: A Study in CCK-A Receptor Gene Knockout Mice[J]. Digestive Diseases and Sciences . 2003 (10)
  • 10Yan-Shi Guo,Courtney M. Townsend Jr.Roles of gastrointestinal hormones in pancreatic cancer[J]. Journal of Hepato - Biliary - Pancreatic Surgery . 2000 (3)

共引文献14

同被引文献92

引证文献7

二级引证文献105

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部