临床药师对1例胰十二指肠切除术后腹腔感染患者的药学监护

Pharmaceutical Care for One Case of Complicated Intra-abdominal Infection after Pancreatoduodenectomy

目的:分享术后腹腔感染的抗感染治疗经验。方法:对临床药师参与的1例胰十二指肠切除术后感染患者的用药全过程进行回顾性分析讨论。结果:血培养和腹腔积液均培养出肠球菌,临床药师结合药敏结果提出用药建议并进行用药监护,根据血药浓度调整万古霉素剂量,根据病情变化更换治疗方案,及时控制了不良反应的发生发展,最终取得良好治疗效果。结论:术后复杂性腹腔感染的病原学复杂,治疗较为棘手,临床药师的参与提高了救治的有效率和安全性。

Objective： To share the anti-infection experience for the patients with complicated intra-abdominal infection after oper- ation. Methods： The whole course of drug administration participated by clinical pharmacist in one patient with complicated intra-ab- dominal infection after pancreatoduodenectomy were retrospectively analyzed and discussed. Results： Enterococcus was found in the blood culture and ascites. According to the results of drug sensitive tests, clinical pharmacist provided medication suggestions and per- formed medication mornitoring. According to the blood concentration, clinical pharmacist adjusted the dose of vancomycin, and changed the therapy regimen according to the changes of conditions. As a result, adverse reactions were controlled timely, and satisfac- tory treatment effects were obtained. Conclusion： The aetiology of complicated intra-abdominal infection is complex with intractable treatment, and the participation of clinical pharmacists in the treatment can improve the efficiency and safety.