咽炎灵分散片中药材提取工艺考察

Study on the Extraction Technology of Medicinal Materials in Yanyanling Dispersible Tablets

目的:优选咽炎灵分散片中药材的最佳提取工艺。方法:以提取液中没食子酸的含量和总固体得率的综合评分为指标,采用正交设计试验考察液料比、提取时间和提取次数三因素对咽炎灵分散片中药材提取率的影响。结果:最佳提取工艺条件为:料液比1∶10(g·ml^(-1))、提取时间1 h,提取次数3次。结论:在最佳提取工艺条件下,咽炎灵分散片中药材中没食子酸的提取率为0.058%,总固体得率为21.4%,优选的工艺稳定可行,可为咽炎灵分散片的生产提供参考。

Objective： To optimize the extraction technology of Chinese medicinal materials in Yanyanling dispersible tablets. Methods ： Orthogonal design was used to study the effects of three factors, including the ratio of liquid to materials, extraction time and extraction times on the extraction rate of Chinese medicinal materials and the comprehensive score of gallic acid content and total solid yield was used as the index. Results： The optimum extraction conditions were as follows ： the ratio of materials to liquid was 1 ： 10 （ g·ml-1 ）, the extraction time was one hour, and the extraction times was three. Conclusion： Under the optimum conditions, the ex- traction rate of gallic acid in Chinese medicinal materials in Yanyanling dispersible tablets is 0.058%, and the total solid yield is 21. 4%. The optimal process is stable and feasible, which can provide reference for the production of Yanyanling dispersible tablets.