摘要
Genomes have been studied by biologists for decades with a goal to decipher the origin,evolution,and nature of life on earth.These studies often rely on genetic manipulations such as deletions and insertions(a top-down approach),but recent advances in DNA synthesis provide a new option—whole genome synthesis(a bottom-up approach).While several bacterial and viral genomes have been
Genomes have been studied by biologists for decades with a goal to decipher the origin,evolution,and nature of life on earth.These studies often rely on genetic manipulations such as deletions and insertions（a top-down approach）,but recent advances in DNA synthesis provide a new option—whole genome synthesis（a bottom-up approach）.
