磁共振扩散加权成像在直肠癌新辅助放化疗中的应用价值

Diffusion-Weighted Imaging in Neoadjuvant Chemoradiotherapy for Rectal Cancer

新辅助放化疗已成为直肠癌术前常规治疗手段,具有降低直肠癌分期、提高直肠癌保肛率、减少直肠癌局部复发及可能达到病变完全缓解等优势。磁共振扩散加权成像(diffusion-weighted imaging,DWI)能够反映肿瘤分子功能信息,可较好地评估直肠癌新辅助放化疗的疗效,本文对DWI在直肠癌新辅助放化疗后早期疗效监测、肿瘤残余、临床及病理缓解等方面的价值及其局限性进行综述。

Preoperative neoadjuvant chemoradiotherapy is a routine treatment for rectal cancer. It helps to reduce rectal cancer staging, improve anus preservation rate, reduce local recurrence and achieve complete response. Diffusion-weighted imaging （DWI） provides information of molecular function of tumor. It can be used to evaluate the effect of neoadjuvant chemoradiotherapy treatment for rectal cancer. The value of DWI in preoperative neoadjuvant chemotherapy of patients with rectal cancer including monitoring early stage of therapy effect, tumor remnants,clinical and pathological response, as well as its limitations are focused in this review.