泛发性脓疱型银屑病合并亚急性皮肤型红斑狼疮一例

A Case of Generalized Pustular Psoriasis Complicated with Subacute Cutaneous Lupus Erythematosus

泛发性脓疱型银屑病(generalized pustular psoriasis,GPP)是一种以皮肤大面积红斑、脓疱、发热、白细胞增多为主要表现且反复发作的系统性炎症性疾病。亚急性皮肤型红斑狼疮(subacute cutaneous lupus erythematosus,SCLE)是介于盘状红斑狼疮和系统性红斑狼疮之间的自身免疫性疾病,两者并发少见。本文报道一例GPP合并SCLE病例,分析其临床表现、实验室检查结果及两种疾病并发的原因。

Generalized pustular psoriasis （ GPP） is a systemic inflammatory disease with recurrent episodes of erythema, pustules,fever and leukocytosis. Suhacute cutaneous lupus erythematosus （ SCLE） is an autoimmune disease hetween discoid lupus erythematosus and systemic lupus erythematosus. Coexistence of the two diseases is uncommon. Here we report a case of generalized pustular psoriasis comhined with suhacute skin lu-pus erythematosus. The clinical manifestations and lahoratory results are presented and the possihle reasons for co-existence are discussed.