小儿脑性瘫痪共患癫痫研究进展

Research progress of pediatric cerebral palsy with epilepsy

脑性瘫痪是导致儿童残疾最常见的病因。癫痫是儿童神经系统常见的慢性疾病，癫痫在脑性瘫痪中的发病率较普通儿童明显升高。癫痫是脑性瘫痪常见的并发症，且脑性瘫痪共患癫痫常为难治性癫痫。癫痫及发作间期的痫性放电会加重脑性瘫痪患儿的脑损伤，其对脑性瘫痪的影响不容忽视。脑性瘫痪共患癫痫（或发作间期痫性放电）提示病情加重，及时有效地控制脑性瘫痪患儿的癫痫发作（或发作间期痫性放电）可减少患儿的脑损害，促进患儿康复，改善患儿预后。

Cerebral palsy is the most common cause of physical disability in children. Epilepsy is one of the common chronic nervous diseases in children＇s nervous system, the prevalence of which is significantly higher than that in general children. Epilepsy is considered one of the most common complications of cerebral palsy, and some of which are refractory epilepsy. Epileptic seizures and interictal epileptiform discharges （IEDs） can aggravate brain damage in children with cerebral palsy, and their effects on cerebral palsy can not be ignored. Epilepsy or IEDs were found to be predictors of poor cerebral palsy outcome. It is necessary to timely and effectively control seizures or IEDs, which can not only reduce brain damage, but also promote their rehabilitation and prognosis.