SEEDi：动脉粥样硬化性心血管病一二级预防的基本策略

SEEDi:Basic strategies for the primary and secondary prevention of atherosclerotic cardiovascular disease

目前国内外对于动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)一二级的预防主要基于药物和改善生活方式的ABCDE策略,或称"药物为主型策略"。作者2005年提出的由"四大健康要素"[睡眠(sleep)、情绪(emotion)、运动(exercise)和饮食(diet)]构成的非药物且健康的"种子(SEED)"法则,或称SEED干预(SEEDi)策略是指导慢性非传染性疾病,特别是指导ASCVD的一二级预防的基本策略。大力推广SEEDi策略,将使我国ASCVD等慢性病的防治实现"三大转变":由被动型向主动型转变、由如何治向如何防转变、由住院治疗向家庭保健转变,从而形成我国ASCVD防治花费少、效果好的新局面,使ASCVD发病率和病死率明显下降,疾病预后和患者生活质量显著改善。

ABCDE strategy, mainly based on drugs or medications and the lifestyle modification （named as ＂main medical strategy＂）, is popular in the guideline for primary and secondary prevention of atherosclerotic cardiovascular disease （ASCVD） in China and foreign countries. Here, the author recommends a non-invasive and non-pharmacologic ＂Zhongzi＂ rule, which includes 4 healthy elements： Sleep, emotion, exercise, and diet （SEED）, and also called SEED intervention （SEEDi） strategy. It is the basic strategy for primary and secondary prevention of non-infectious diseases, especially for ASCVD. The strategy of SEEDi could decrease ASCVD morbidity and mortality. If the strategy of SEEDi is conducted positively and widely in the clinical work, it will achieve ＂three major changes＂ for ASCVD： From passive to active, from how to treat to how to prevent, and from hospital treatment to home care. It will create a new situation with less costs and better effects in ASCVD prevention and treatment in China. The morbidity and mortality for ASCVD will decrease significantly, and the prognosis and quality of life （QOL） will be improved significantly.