综合性护理在伴Hp感染急性脑梗死患者治疗中的应用

Application of Comprehensive Intensive Nursing Intervention in the Treatment of Acute Cerebral Infarction with Helicobacter Pylori Infection

目的探讨综合性护理在伴幽门螺杆菌(Hp)感染急性脑梗死患者治疗中的应用价值。方法 72例伴Hp感染的急性脑梗死(ACI)患者随机分为综合性护理组(n=36)和常规护理组(n=36),均给予抗Hp的三联疗法和溶栓抗凝、抗血小板聚集等脑梗死常规综合治疗,对照组给予常规护理,观察组给予综合性强化护理干预,比较两组Hp根除率及神经功能缺损评分(NIHSS),检测两组护理前后凝血功能指标及血小板活化率,并统计治疗依从性和护理满意度等。结果强化护理组Hp根除率88.89%明显高于对照组69.44%,护理后NIHSS评分显著低于对照组(P<0.05)。两组护理前各项凝血功能指标及血小板活化百分率比较无统计学意义(P>0.05),护理后与对照组比较,强化护理组凝血酶原时间(PT)、活化部分凝血活酶时间(a PTT)、凝血酶时间(TT)明显较长,纤维蛋白原(Fbg)、D二聚体(D-D)、CD62p血小板百分率显著较低(P<0.05)。强化护理组治疗依从性、护理满意度明显高于对照组,合并症发生率11.11%明显低于对照组30.55%(P<0.05)。结论综合性强化护理干预对改善伴Hp感染急性脑梗死患者的临床治疗疗效和凝血功能有积极作用。

Objective To investigate the value of comprehensive intensive nursing intervention in the treatment of acute cerebral infarction with Helicobacter pylori（Hp） infection. Methods A total of 72 patients with acute cerebral infarction with Hp infection were randomly divided into the intensive nursing group （n = 36） and the control group （n = 36 ）. All patients were given routine comprehensive therapy for cerebral infarction. The control group were given routine nursing, and the intensive nursing group were given comprehensive intensive nursing intervention. The Hp eradication rate and neurological impairment score （NIHSS） were compared between the two groups. The indexes of coagulation function and platelet percentage in the two groups were detected before and after nursing. Results The Hp eradication rate in the intensive nursing group（88.89% ）was higher than that in the control group （69.44%）, and the NIHSS score was significantly lower than that of the control group （P 〈 0. 05）. There was no significant difference in indexes of blood coagulation and platelet percentage between the two groups before nursing （ P 〉 0. 05 ）. After nursing, compared with the control group, the prothrombin time（1：0＂）, activated partial thromboplastin time （atYfT）and thrombin time （TY）of the intensive nursing group was significantly longer, while fibrinogen （Fbg）, D-direct（ D- D） and CD62p platelet percentage were significantly lower（P 〈0. 05）. The treatment compliance and nursing satisfaction of the intensive nursing group were significantly higher than those of the control group, and the incidence of complications（ 11.11% ）was significantly lower than the control group（30.55% ）（ P 〈0. 05 ）. Conclusion Comprehensive intensive nursing intervention play an positive role in improving the clinical efficacy and blood coagulation function in patients with acute cerebral infarction with Hp infection, and it also can significantly improve the satisfaction of patients.