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S100A8/A9在2型糖尿病及其并发症中的作用及意义 被引量:5

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摘要 S100A8/A9,又称钙卫蛋白,是一种钙-锌结合蛋白质,主要由单核细胞,中性粒细胞和分化早期的巨噬细胞分泌,具有多种生物学功能。目前对于钙卫蛋白与疾病的相关研究有很多,除了发现钙卫蛋白与肿瘤、多种炎症性疾病及自身免疫性疾病密切相关,还发现在肥胖、2型糖尿病(type 2 diabetes mellitus,T2DM)及其并发症患者体内,S100A8/A9也呈高表达,但其机制至今尚未阐明。现就钙卫蛋白与T2DM及其并发症的研究作一综述。
出处 《华南国防医学杂志》 CAS 2017年第4期280-282,共3页 Military Medical Journal of South China
基金 国家自然科学基金资助项目(81173620)
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