真武汤加味治疗脾肾阳虚型慢性肾小球肾炎疗效观察

Clinical Curative Effect of Modified Zhenwu Decoction Used in Treating Spleen-deficiency Type Chronic Glomerulonephritis

目的:观察真武汤加味治疗脾肾阳虚型慢性肾小球肾炎临床疗效。方法:选择在我院就诊的60例脾肾阳虚型慢性肾炎患者,利用随机数值法分为对照组及治疗组,每组30例。对照组使用常规西医治疗方式,治疗组在对照组的治疗方式上加用真武汤加味。对比试验前后两组患者的尿红细胞个数、24小时尿蛋白排泄量(24hupq)、肾功能指标(Bun、Scr)等指标,分析两组治疗前后的有效率和临床症状的改善情况。结果:治疗组试验后24hupq、Bun、Scr、尿红细胞个数等指标均明显优于对照组,差异具有统计学意义(P<0.05);治疗组试验后患者的主要临床症状的改良情况明显比对照组好,差异具有统计学意义(P<0.05);治疗组有效率86.7%高于对照组有效率56.7%,差异具有统计学意义(P<0.05)。结论:真武汤加味治疗脾肾阳虚型慢性肾小球肾炎患者具有显著的疗效。

Objective： To investigate the clinical effect of Modified Zhenwu Decoction for treating spleen deficiency type of chronic glomernlonephritis. Methods ： Selected 60 cases of patients with spleen-kidney Yang-deficiency type of chronic nephritisin in our hospital as research objects. And divided them into controlled group and treatment group according to the random nu- merical method, 30 cases of patients in each group. The controlled group was treated with conventional western medicine, and the treatment group was added Zhenwu Decoction based on the controlled group. Compared the number of red blood cells, 24h u- rinary protein excretion （24hupq） and renal function indexes （Bun, Scr） between the two groups of patients before and after the treatment. Analyzed the improvement of efficiency and clinical symptoms of the two groups. Results： 24hupq, Bun, Scr, urine red blood cell number and other indicators of the treatment group were significantly better than those of the controlled group, and the difference was statistically significant （P 〈 0. 05 ） ; The improvement of main clinical symptoms of the patients in the treat- ment group was significantly better than that of the controlled group, and the difference was statistically significant （ P 〈 0. 05 ） ; The effective rate of the treatment group （86. 7% ） was higher than that of the controlled group （56. 7% ）, the difference was statistically significant （P 〈 0. 05 ）. Conclusion ： Modified Zhenwu Decoction has significant curative effectin treatment of patients with spleen-kidney Yang-deficiency type of chronic glomerulonephritis.