中医药辨证治疗早期糖尿病肾病概况

A Profile About Traditional Chinese Medicine Treatment Based on Syndrome Differentiation of Early Diabetic Nephropathy

整体观念和辨证论治是中医药治疗早期糖尿病肾病(DN)的独特优势。本文从病因、病机、治则、治法等方面对近几年中医药辨证治疗早期DN的进展进行了概括,并强调健脾益肾法在治疗早期DN微量蛋白尿中的意义。中医药能够有效延缓甚至逆转早期DN的发展,明显改善患者生存质量和延长寿命且毒副作用相对较小,但存在辩证分型不统一、样本量小、观察时间短、缺乏中医特色的观察指标等问题。中医症状积分量表和中医诊疗仪器的应用有可能提供中医特色的观察指标,从而明确验证其临床疗效。

The overall concept and treatment based on syndrome differentiation are unique advantages of traditional Chinese medicine （TCM） in treatment of early diabetic nephropathy （DN）. In this paper, the progress about TCM treatment based on syndrome differentiation of early DN has been summarized from etiology, pathogenesis, therapeutic method to treatment principle and so on in recent years, and emphasizes the meaning that the method of strengthening spleen and invigorating kidney treatments trace albuminuria of early DN. TCM can effectively slow down even reverse the development of early DN, significantly improve the patients quality of life and prolong life-span and the side effects are relatively small but there are a few problems that the dia- lectical classification is not unified, the sample size is small, observation time is short and lacks of the observation index reflects the characteristics of TCM and so on. TCM symptoms integral scale and instrument application may provide observation indexes of TCM, thus clearly verify its curative effect.