变应性鼻炎与变应性结膜炎的相关性进展研究

The correlation research progress of allergic rhinitis and allergic conjunctivitis

变应性鼻炎与变应性结膜炎均是由外源性抗原引起的免疫性疾病,具有变应性体质的病人与超敏原初次接触后,会使病人处于致敏状态,当再次接触该超敏原时,病人机体便会产生某些蛋白质因子以及细胞因子,促使变应性疾病的发生发展。临床上常见变应性鼻炎病人除鼻塞、喷嚏及清水样鼻涕等典型症状以外,还伴随着变应性结膜炎的症状,例如眼红、眼痒、迎风流泪及水样分泌物等症状。目前国内外专家在多个层面上分别对变应性鼻炎及变应性结膜炎的病因、发生机制以及治疗进行了一定的研究。该研究主要从两者的相关性方面进行概述,希望对临床研究及综合治疗变应性疾病具有指导意义。

Allergic rhinitis and allergic conjunctivitis is autoimmune disease caused by exogenous antigens. With allergic constitution, the patient would in a state of sensitization when contacted with allergic original at first time. When contacted the allergic original again, it can make the body produce some protein and cytokines, prompting the occurrence of allergic disease development. Clinically, we con-tact with the patients of common allergic rhinitis have the symptom such as nasal congestion, sneezing and watery stuff, accompanied with allergic conjunctivitis symptoms such as jealous,eye itch,tears and water discharge in the breeze. At present,the etiology and treat-ment of allergic rhinitis and conjunctivitis have been studied from some aspects. This article reviews relationship of allergic rhinitis and allergic conjunctivitis which would contribute to new research progress of clinical comprehensive treatment of allergic disease.