未足月胎膜早破期待时间长短对妊娠结局的影响

The effect of the expected time of preterm premature rupture of membranes on pregnancy outcome

目的:研究分析未足月胎膜早破发生后期待时间的长短对妊娠结局的影响。方法:收治住院分娩的未足月胎膜早破孕妇120例,根据怀孕时间分两组,比较两组未足月胎膜早破孕妇期待时间长短及孕妇和早产儿并发症发生情况的差异。结果:孕28~33+6周组孕妇绒毛膜羊膜炎、新生儿呼吸窘迫、早产儿死亡及缺血缺氧性脑病发生率均显著高于孕34~36+6周组(P<0.05);孕28~33+6周组期待时间2 d以内的新生儿呼吸窘迫、缺血缺氧性脑病发生率均显著高于期待时间超过2 d者(P<0.01)。结论:临床上应对孕28~33+6周未足月胎膜早破孕妇实施促进胎肺成熟和预防感染等措施,适当延长孕周而改善围生儿预后;孕34~36+6周未足月胎膜早破、胎肺已成熟的孕妇不应继续保胎,应在破膜2 d内终止妊娠。

Objective:To analyze and study the effect of the expected time of preterm premature rupture of membranes on pregnancy outcome.Methods:120 cases of preterm premature rupture of membranes were selected.They were divided into the two groups according to the time of pregnancy.The expected time of preterm premature rupture and the complications of pregnant women and premature infants in the two groups were compared.Results:The incidence of chorioamnionitis,neonatal respiratory distress,premature infant death and ischemic hypoxic encephalopathy were significantly higher in pregnant women from 28~33+6weeks of gestation than those from the gestational age group of 34~36+6(P<0.05).The incidence of neonatal respiratory distress and ischemic hypoxic encephalopathy within 2 days was significantly higher than that of the expected time of more than 2 days in the pregnancy 28~33+6weeks group(P<0.01).Conclusion:In the clinical treatment of preterm premature rupture of membranes in women with 28~33+ 6weeks pregnancy,they should given promote fetal lung maturation and prevention measures,appropriate prolonged gestational age to improve perinatal prognosis,34~36+6gestational weeks before termpremature rupture of membranes and fetal lung mature pregnant women should not continue to miscarriage,and it should be in the rupture of membranes within 2days to terminate the pregnancy.