吉林市地区石化行业接触性皮炎患者过敏原的临床研究

Investigation of allergens of contact dermatitis of patients in the petrochemical industry in Jilin

目的:调查吉林市地区石化行业引起接触性皮炎的主要致敏原。方法:收集196例接触性皮炎患者进行过敏原检测,统计不同性别、年龄及职业部门各种致敏原的阳性率。结果:196例接触性皮炎患者总阳性率84.69%,阳性率居前的致敏原分别为洗涤剂、硫酸镍、甲醛、氨/氯气、重铬酸钾、苯及衍生物。不同性别、年龄、职业部门其致敏原阳性率各有差异。结论:洗涤剂、硫酸镍、甲醛、氨/氯气、重铬酸钾、苯及衍生物为接触性皮炎的主要致敏原;性别、年龄、职业部门等因素对致敏原阳性率均有影响。

Objective： To investigate the major allergens of contact dermatitis of patients in the petrochemical industry in Jilin city. Methods： 196 patients with contact dermatitis were collected and given the allergen test. The positive rates of the patients with different genders, ages and occupations were statistically analyzed. Results： The total positive rate of the 196 patients with contact dermatitis was 84. 7%. The allergens with the higher positive rates were washing agents, Nickel sulfate, Formaldehyde, Ammonia/ Chlorine, Potassium dichromate, Benzene and its derivatives. The allergen positive rates were different among the patients with different genders, ages and occupations. Conclusions： The major allergens of contact dermatitis are washing agents, Nickel sulfate, Formalde-hyde, Ammonia/ Chlorine, Potassium dichromate, Benzene and its derivatives. Moreover, the allergen positive rate is affected by the factors such as genders, ages and occupations.