摘要
本文旨在探讨胃癌患者术前发生营养不良的原因、诊断方法和营养不良与胃癌预后的关系,为临床医师对胃癌患者术前诊断营养不良、改善临床结局提供指导。以"胃癌"、"营养不良"等作为关键词在CNKI和Pubmed中查阅相关文献,对胃癌患者术前营养不良的定义、诊断方法、胃癌患者发生营养不良的原因、营养不良与胃癌患者预后的关系、营养不良的诊断与治疗在胃癌加速康复外科临床应用的价值等方面进行归纳总结。研究结果提示,首先,胃癌患者术前可通过营养筛查、营养评估、综合测定的方法诊断营养不良并实施营养治疗。其次,能量摄入、吸收和利用减少,炎性和应激水平增高以及代谢紊乱,是胃癌患者术前发生营养不良的主要原因,并且营养不良是影响胃癌患者预后的危险因素。从而我们发现,联合营养筛查和评估明确诊断营养不良及评估其程度,及时有效地进行营养干预,合理优化营养治疗,可降低术后并发症的发生率和住院费用,缩短总住院时间和术后住院时间,对改善临床预后有重要的意义。
This paper was to investigate the causes of preoperative malnutrition, diagnosis and the relationship between malnutrition and prognosis of gastric cancer, in order to provide guide for clinicians for the diagnosis of malnutrition and improve clinical outcome in patients with gastric cancer.
作者
史波
刘金禄
陈俊强
SHI Bo LIU Jin-lu CHEN Jun-qiang(Department of Gastrointestinal Surgery, The First Affliated Hospital of Guangxi Medical University, Nanning 530021, China)
出处
《肿瘤代谢与营养电子杂志》
2017年第2期221-225,共5页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
国家自然科学基金(81360370)
广西医药卫生基金(Z2015526)
广西自然科学基金(2016GXNSFAA380180)
关键词
胃癌
营养不良
营养筛查
营养评估
加速康复外科
such as “gastric cancer” and “malnutrition” were reviewed in CNKI and Pubmed databases. The definition and diagnosis of preoperative malnutrition in patients with gastric cancer, the causes of preoperative malnutrition in patients with gastric cancer, the relationship between malnutrition and the prognosis of patients, and the value in the clinical application of enhanced recovery after surgery were summarized. The results suggested that, frstly, patients with gastric cancer could be diagnosed by nutritional screening, nutritional assessment, and comprehensive measurement aimed to carry out nutritional therapy. Secondly, the reduction of energy intake, absorption and utilization, the increase of infammatory and stress levels and metabolic disorders were the main causes of preoperative malnutrition in patients with gastric cancer, and malnutrition was the prognostic factor of patients. It was great signifcance to improve the clinical prognosis by combining nutritional screening with nutritional assessment to diagnose malnutrition and evaluate the degree for the sake of nutritional therapy effectively and promptly which could not only reduce the incidence of postoperative complications and hospitalization costs, but also shorten the total length of hospital stay and postoperative hospital stay. Key words Gastric cancer
Malnutrition
Nutritional screening
Nutritional assessment
Enhanced recovery after surgery
