药物联合饮食控制、运动疗法治疗社区老年2型糖尿病的临床疗效研究

Clinical effect study of drug combined with diet control,exercise therapy in the treatment of elderly community diabetes mellitus type 2

目的探讨药物联合饮食控制、运动疗法治疗社区老年2型糖尿病(2-DM)的临床疗效。方法选取厦门市湖里区殿前街道社区卫生服务中心2014年6月—2015年8月收治的老年2-DM患者96例,采用随机数字表法分为对照组与研究组,各48例。对照组予以药物治疗,研究组在对照组基础上予以饮食控制、运动疗法治疗,两组患者均持续治疗3个月。比较两组患者的临床疗效、治疗前后空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平、健康检查量表(SF-36)评分及不良反应发生情况。结果研究组患者临床疗效优于对照组(P<0.05)。治疗前两组患者FPG、2 h PG、HbA_(1c)水平比较,差异无统计学意义(P>0.05);治疗后研究组患者FPG、2 h PG及HbA_(1c)水平低于对照组(P<0.05)。治疗前两组患者SF-36评分比较,差异无统计学意义(P>0.05);治疗后研究组患者SF-36评分高于对照组(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论药物联合饮食控制、运动疗法治疗社区老年2-DM的临床疗效确切,可有效稳定患者的血糖水平,提升生活质量。

Objective To study the clinical effect of drug combined with diet control,exercise therapy in the treatment of elderly community diabetes mellitus type 2（2-DM）.Methods A total of 96 cases of elderly patients with 2-DM were selected from June 2014 to August 2015 in Dianqian Street Community Health Service Center of Huli District in Xiamen,which were randomly divided into control group and study group,48 cases in each group.The control group was treated with drug therapy,study group was given diet control,exercise therapy on the basis of control group,both groups were treated for 3 months.The clinical effect,FPG,2 h PG,HbA1c and SF-36 scores before and after treatment and the incidence of adverse reactions were compared between the two groups.Results The clinical effect of study group was better than control group（P〈0.05）.Before treatment,no statistically significant differences of FPG,2 h PG or HbA1c levels was found between the two groups（P〉0.05）;after treatment,the study group of FPG,2 h PG and HbA1c levels were lower than control group（P〈0.05）.Before treatment,no statistically significant difference of SF-36 scores was found between the two groups（P〉0.05）;after treatment,the study group of SF-36 scores were higher than control group（P〈0.05）.No statistically significant differenc of the incidence of adverse reactions was found between the two groups（P〉0.05）.Conclusion Drug combined with diet control,exercise therapy have an exactly clinical effect in the treatment of elderly community 2-DM patients,it can effectively stable the blood glucose level of patients,and improve the quality of life.