山东某医院抗高血压药物使用情况分析

Analysis of antihypertensive drugs use in one hospital of Shandong Province

目的探讨山东某医院抗高血压药物使用情况。方法通过采用回顾性分析方法,对山东某医院2014年5月至2015年5月1年中抗高血压药物种类、规格、销售数量、销售金额、用药频度(DDDs)及限定日费用(DDDc)进行统计分析。结果钙拮抗剂的销售量及销售金额处于第1位;1年中出库量最多的是肾上腺素受体阻断药美托洛尔;出库量排序前15位抗高血压药物中钙拮抗剂有4种,血管紧张素II受体阻滞剂(ARB)有3种,血管紧张素转换酶抑制剂(ACEI)有3种,肾上腺素受体阻断药有2种,血管扩张剂有1种,利尿剂有1种,复方制剂(厄贝沙坦氢氯噻嗪)有1种;钙拮抗剂类抗高血压药物的DDDs最大,其次为ARB;患者选择倾向最大的前3位药物是ARB型缬沙坦、肾上腺素受体阻断药美托洛尔、钙拮抗剂尼莫地平;其中呋塞米的DDDc最低,缬沙坦的DDDc最高。结论钙拮抗剂的出库量、金额及DDDs值均位于七类抗高血压药物之首,其次为ARB,周围血管扩张剂及中枢性降压药物用量较少。

Objective To investigate the use of antihypertensive drugs in a hospital in Shandong.Methods By using retrospective analysis method, to a hospital in Shandong from May 2014 to May 2015 1 years of anti hypertension drug types,specifications,sales volume,sales amount,DDDs and defined daily cost to carry out statistical analysis.Results Sales volume and sales amount of calcium antagonists in first;from 1 years up to the amount of beta blocker Mei TORO M;sales top 15 anti hypertensive drugs calcium antagonist 4,angiotensin II receptor blockers have 1 kinds,1 kinds of compound preparation of diuretics,（irbesartan and hydrochlorothiazide） 1;calcium antagonist there are 3 kinds of angiotensin converting enzyme inhibitor （ACEI） 3,there are 2 kinds of beta blockers,vasodilators anti hypertension drugs DDDs is the largest,followed by ARB;patients tend to choose the top 3 largest drug is ARB valsartan,beta blockers,calcium antagonist nimodipine Mei TORO M;the furosemide DDDc minimum,valsartan had the highest DDDc.Conclusion The amount of ARB,the amount and the DDDs value of the calcium antagonist were located in the first of the seven types of antihypertensive drugs,followed by a small amount of peripheral vasodilators and central antihypertensive drugs.