摘要
Novel fluorescent coumarin-4H-pyran conjugates were achieved by three-component reactions of various synthetic β-ketoesters with aldehydes and malononitrile in aqueous media.Besides mild reaction conditions,operational simplicity,absence of tedious separation procedures,using of inexpensive and nontoxic commercially available cationic surfactant cetyltrimethylammonium chloride（CTAC） as a catalyst are the prominent advantage of this method.
Novel fluorescent coumarin-4H-pyran conjugates were achieved by three-component reactions of various synthetic β-ketoesters with aldehydes and malononitrile in aqueous media.Besides mild reaction conditions,operational simplicity,absence of tedious separation procedures,using of inexpensive and nontoxic commercially available cationic surfactant cetyltrimethylammonium chloride（CTAC） as a catalyst are the prominent advantage of this method.
基金
the financial support from the National Natural Science Foundation of China(No.21462041)
Natural-Science Foundation for Distinguished Young Scholars of Xinjiang Uyghur Autonomous Region(No.Qn2015jq002)
the Tianshan Talent Cultivation Project of Xinjiang Uyghur Autonomous Region
