“脏腑之精化生脏腑之气”的现代医学机制

Modern Medicine Mechanism of “Essence of Zang-Fu Organs Turning into Qi of Zang-Fu Organs”

依据"脏腑之精"和"脏腑之气"的内涵,提出了中医"脏腑之精化生脏腑之气"的现代医学本质的假说。"脏腑之精"的现代医学本质主要体现为脏腑的所有细胞和由细胞外基质、组织液及细胞间信号分子等组成的细胞微环境的有机集合;而"脏腑之气"的现代医学本质主要涉及不断运动、相互作用、共同完成分子水平做功或能量转化的细胞特殊蛋白质、生物小分子及三磷酸腺苷。在上述假说的基础上,通过阐述"脏腑之精化生脏腑之气"的现代医学机制,揭示其现代医学原理,探讨补气中药通过影响细胞信号传导途径发挥补气功效的作用机理。

This article suggests the hypothesis of the modern medicine nature of ＂essence of Zang-Fu organs＂ and ＂Qi of Zang-Fu organs＂ in Chinese medicine based on their connotation. The nature of the ＂essence of Zang-Fu organs＂ in modern medicine mainly manifests in the organic collection of all the cells of Zang-Fu organs and the cellular microenvironment including extracellular matrix, tissue fluid and intercellular signaling molecules etc. , while the nature of ＂Qi of Zang-Fu organs＂ in modern medicine primarily involves some special proteins, small biomolecules and adenosine triphosphate （ATP） that keep moving, interact with each other and work together in molecular level for energy transformation. Based on the aforementioned hypothesis, this article suggests the modern medicine principle of the essence of Zang-Fu organs turning into Qi of Zang-Fu organs, via stating the modern medicine mechanism of the ＂essence of Zang-Fu organs turning into Qi of Zang-Fu organs＂. It also discusses the modern medicine mechanism of Qi-supplementing Chinese herbs supplementing Qi through cellular signaling pathways.