不同配比药物艾条温和灸治疗风寒湿证神经根型颈椎病400例临床观察

Clinical Observation on 400 Cases of Cervical Spondylotic Radiculopathy of Wind-Cold-Damp Syndrome Treated with Warming Moxibustion Using Moxa Stick with Different Herbal Components

目的观察不同组成药艾条对400例神经根型颈椎病患者的临床疗效。方法将400例风寒湿证神经根型颈椎病患者随机分为治疗组(药艾条,正常比例)、清艾组(仅用艾绒)、对照组1~6(分别使用药艾条按不同比例制备的拟药艾条)各50例,进行温和灸治疗,各组均每两日艾灸1次,共90天。观察各组临床疗效以及临床神经病理性疼痛量表(NPQ)百分比和视觉模拟评分法(VAS)评分改善情况。结果治疗组、清艾组、对照组1、对照组2、对照组3、对照组4、对照组5、对照组6临床疗效总有效率分别为98.0%、84.0%、78.0%、70.0%、62.0%、88.0%、84.0%及82.0%,治疗组总有效率明显高于清艾组及对照组1~6(P<0.05或P<0.01),清艾组及对照组4、5、6总有效率明显高于对照组3(P<0.05或P<0.01)。各组患者治疗后NPQ百分比及VAS评分均明显下降(P<0.05或P<0.01);治疗后治疗组NPQ百分比及VAS评分均明显低于清艾组及对照组1~6(P<0.01);治疗后清艾组及对照组1、4、5、6 NPQ百分比及VAS评分明显低于对照组3(P<0.05或P<0.01)。结论药艾条对风寒湿引起的神经根型颈椎病临床疗效较好,以艾绒联合三种中药效果最佳。

Objective To observe the clinical efficacy treatment of 400 cases of cervical spondylotic radiculopathy. of moxa stick with different herbal components in the Methods Four hundred cases of cervical spondylotic radiculopathy with wind-cold-damp syndrome were randomly divided into treatment group （moxa stick with herbs, normal proportion）, pure moxa stick group （ only moxa） and control groups 1 to 6 （ analogous moxa stick made of different proportions of herbs）, with 50 cases in each group. Each group was given mild-warm moxibustion once every two days for 90 days. The clinical efficacy, as well as the improvement of percentage of neuropathic pain question- naire （NPQ） and visual analogue scores （VAS） of each group were observed. Results The total effective rate of the efficacy in treatment group, pure moxa stick group, control group 1, control group 2, control group 3, control group 4, control group 5 and control group 6 was 98.0%, 84. 0%, 78.0%, 70. 0%, 62. 0%, 88.0%, 84. 0% and 82.0%, respectively. The total effective rate in treatment group was significantly higher than that in pure moxa stick group and in control group 1 to 6 （ P 〈 0. 05 or P 〈 0. 01 ）. The total effective rate in pure moxa stick group and con- trol group 4, 5, 6 were significantly higher than that in control group 3 （P 〈 0. 05 or P 〈 0. 01 ）. The percentage of NPQ and VAS score in each group were both decreased after treatment compared with those before treatment （P 〈 0. 05 or P 〈 0. 01 ）. After treatment, the percentage of NPQ and VAS score in treatment group were both significantly lower than those in pure moxa stick group and the control group 1 to 6 （P 〈0. 01 ）, and the percentage of NPQ and VAS score in pure moxa stick group and control group 1,4, 5, 6 were significantly lower than those in control group 3 （P 〈 0. 05 or P 〈 0. 01 ）. Conclusion Medicinal moxa stick seems to have better clinical effect in the treatment of cervical spondylotic radiculopathy with wind-cold-damp syndrome. Moxa combined with three Chinese herbs seem to have the best clinical effect.