几种兽用合成抗菌药基于抗体快速检测技术研究进展

Research Progress on Antibodies Rapid Detection Technology for Veterinary Synthetic Antibacterial Agents

合成抗菌药在预防、治疗动物疾病等方面应用十分广泛,但不合理使用造成的耐药及残留问题日益严重,因此对兽用合成抗菌药的残留检测势在必行,而基于抗体的快速检测技术具有简便、灵敏度高、成本低等优点,发展前景十分广阔。作者综述了近年来针对磺胺类、氟喹诺酮类、喹噁啉类、硝基呋喃类、硝基咪唑类5大类兽用合成抗菌药物的抗体检测技术最新研究趋势,旨在促进残留快速检测技术的发展。

Synthetic antibacterial agents are widely used in prevention and treatment of animal diseases. However, the irrational drugs use has caused severe drug residues issues and bacteria resistance. There- fore, it is particularly important to develop the rapid detection technology. The antibodies rapid detection technology has broad prospects because of its high sensitivity, simplicity, and low cost. The author re- viewed the latest research on antibodies preparation and rapid detection methods for sulfonamides, fluoro- quinolones, quinoxalines, nitrofurans and nitroimidazoles. It is great significant for the development of antibody rapid detection methods on the veterinary drug residues.