早产儿视网膜病变危险因素研究进展

Research progress on risk factors of retinopathy of prematurity

早产儿视网膜病变(retinopathy of prematurity,ROP)是一种视网膜血管增生性疾病,近年来随着医疗水平的不断提高,其发病率也显著增高,该病已成为我国儿童致盲的主要原因之一。目前其发病机制尚不清楚,认为早产、低出生体质量和吸氧是该病的三大危险因素。本文就可能引发该病的多个因素进行综述,旨在扩充ROP的病因和发病机制,为该病的防治提供理论依据。

Retinopathy of Prematurity is a retinal vascular proliferative disease. With the improvement of the medical care in China, retinopathy of prematurity （ROP） has become one of the main causes of child hood blindness in recent years. Several factors such as short gestational age, low birth weight and oxygen supplementation are the three major risk factors for the disease, however, the pathogenesis is still not clear. This review here aims to expand the etiology and pathogenesis of ROP and provide a theoretical basis for the prevention and control of the disease.