摘要
目的:分析农村中老年人群高甘油三酯腰围(HTGW)、2型糖尿病(T2DM)的流行现状及两者间的关联。方法:采用整群抽样的方法于2013年和2014年的7~8月对河南某农村地区45~75岁的中老年人群进行横断面调查,收集其人口统计学特征、行为危险因素、人体测量指标和空腹血标本,并进行血糖和脂质谱的检测。结果:共纳入10 218名研究对象,其中男性3 836人(37.54%),中位年龄56.62岁。HTGW共2 845人(27.84%),男性646人(16.84%),女性2 199人(34.46%)。T2DM共1 406人(13.76%),男性469人(12.23%),女性937人(14.68%)。在调整了年龄、血压、吸烟、饮酒、家族史、体力活动、体重指数(BMI)、高密度脂蛋白后,logistic回归分析结果显示与腰围和甘油三酯水平均正常的人群相比,HTGW可增加T2DM的发病风险,其OR(95%CI)为3.810(3.050~4.760)。以性别和BMI为分层变量分析发现,HTGW与T2DM的关联女性高于男性、18.5≤BMI<24.0kg/m^2人群高于24.0≤BMI<28.0 kg/m^2人群。结论:该农村地区中老年人群HTGW和T2DM的患病率较高,HTGW是T2DM稳定的危险因素。
Aim: To assess the prevalence and relationship between hypertriglyceridemia-waist( HTGW) and type 2diabetes mellitus( T2DM) among middle-aged and elderly residents in the rural area of Henan Province. Methods: A population-based cross-sectional study was conducted in middle-aged and elderly residents aged 45 to 75 years in a rural area of Henan Province from July to August of 2013 and 2014. Demographic characteristics,behavioral risk factors and biochemical indexes were collected in this study. Results: Among the 10 218 subjects,3 836( 37. 54%) were males,and the median age was 56. 62 years. There were 2 845 cases( 27. 84%) of HTGW( male 16. 84%,female 34. 46%) and 1 406 cases( 13. 76%) of T2DM( male 12. 23%,female 14. 68%). After adjusting age,blood pressure,smoking,drinking alcohol,family history,manual labor,BMI and high density lipoprotein,the results of logistic regression analysis showed that,HTGW was the risk factor of T2DM [OR( 95% CI) = 3. 810( 3. 050-4. 760) ]. Stratification analysis according to gender and BMI showed that the association was stronger in females than in males,in 18. 5≤BMI 〈 24. 0 kg/m2 residents than in 24. 0 ≤BMI 〈 28. 0 kg/m2 residents. Conclusion: Among the rural middle-aged and elderly residents,the prevalences of HTGW and T2DM are relatively high,and HTGW is stably and significantly associated with risk of T2DM.
出处
《郑州大学学报(医学版)》
CAS
北大核心
2017年第3期326-330,共5页
Journal of Zhengzhou University(Medical Sciences)
基金
国家自然科学基金资助项目81373074
81402752
关键词
高甘油三酯腰围
2型糖尿病
中老年人群
农村
hypertriglyceridemia-waist
type 2 diabetes mellitus
middle-aged and elderly resident
rural area