新型真菌毒素电化学传感器的研究进展

Research Advances of Electrochemical Sensor for Mycotoxins Detection

真菌毒素是真菌的次级代谢产物,具有极强的毒性,对环境和农作物等均有一定污染性,严重威胁人类健康.为防止其污染的扩大和生物体内富集,对真菌毒素实现实时监测、灵敏检测已成为亟待解决的问题.纳米科学和生物技术的快速发展使得结合了纳米材料、核酸适配体的新型电化学传感器具有非常显著的高特异性、高选择性、简便等优点,对真菌毒素的检测在方法建立和提高灵敏度等方面均有突飞猛进的进展.本文简述了新型电化学传感器对常见真菌毒素检测的研究进展,希望为今后发展更为有效、简便、灵敏的新型电化学传感器提供一定的参考.

Mycotoxins, secondary metabolites produced by toxigenic molds, are widespread and immunosuppressive, carcinogenic, nephrotoxic and teratogenic to human health through food chain cycles. Therefore, there is an urgent require- ment for the detection of mycotoxins. With the development of nanoscience and nanotechnology, the electrochemical bio- sensor, the combination of nanomaterials and aptamer, have aroused increasing attention due to their facile, high specificity and selectivity. In this paper, we summarize the research advances and discuss how to design and construct strategies to de- tect mycotoxins. We expect this review could provide some reference for the development of electrochemical sensor in fu- ture.