凝血四项和血常规在临产孕妇中的变化及临床意义探讨

Changes and Clinical Significance of Blood Coagulation Four Items and Blood Routine in Pregnant Women

目的研究凝血四项在临产孕妇中的变化及临床意义,为凝血四项在临产孕妇中的应用提供有效的参考依据。方法随机选取2015年5月—2016年12月我院收治的临产孕妇168例,设置为实验组,另随机选取同期到医院体检的非妊娠健康女性168例,设置为对照组,给予两组参与人员凝血四项及血常规检验,其中凝血四项的检验项目包括活化部分凝血活酶时间(APTT)、纤维蛋白原(Fib)、凝血酶原时间(PT)、凝血酶时间(TT)等四项,血常规的检验项目包括白细胞计数(WBC)、红细胞计数(RBC)、血红蛋白(HGB)等三项,对两组患者血常规及凝血四项的检查结果进行对比分析。结果实验组人员PT、RBC、TT、APTT、HGB五项检查结果都比对照组的低,而Fib、WBC两项检查结果较对照组高,差异有统计学意义(P<0.05)。结论给予临产孕妇凝血四项检验,有助于医生明确孕妇的身体特征,给予临产孕妇个体化的干预,对于预防母婴并发症有积极作用。

Objective To study the change and clinical significance of four items of blood coagulation in pregnant women, and to provide an effective reference for the application of four items of blood coagulation in pregnant women. Methods Randomly selected 168 cases of pregnant women from May 2015 to December 2016 in our hospital, set up as experimental group, another 168 cases of non pregnant healthy women who were examined at the hospital during the same period were randomly selected as the control group, two groups of four blood coagulation and blood routine tests were performed. The four items of blood coagulation tests including activated partial thromboplastin time （APTT）, fibrinogen （Fib）, prothrombin time （PT）, thrombin time （TT） four, routine blood tests included three counts of white blood cell count （WBC）, red cell count （RBC）, and hemoglobin （HGB）. The results of routine blood test and blood coagulation test in two groups were compared and analyzed between the four groups. Results The test results of PT, RBC, TT, APTT and HGB in the experimental group were lower than those in the control group, while the results of the two tests of Fib and WBC were higher than those of the control group, and the difference was statistically significant （P〈0.05）; the difference between the five groups was statistically signifcant. Conclusion Four tests for blood coagulation in pregnant women are helpful for doctors to make clear the physical characteristics of pregnant women and to give individual intervention to pregnant women in labor, which has a positive effect on preventing maternal and child complications.