摘要
胃癌细胞中存在Epstein-Barr病毒(EpsteinBarr virus,EBV)者被称为EBV相关性胃癌(Epstein-Barr virus-associated gastric carcinoma,EBVaGC).近年来EBVaGC作为一种独特的分子亚型疾病逐渐被人们所认知,全球胃癌患者中平均有10%者为EBVaGC.本文对EBVaGC近年来在流行病学、临床病理特征、发病机制、治疗及预后等方面的研究进展作一综述.但目前对EBVaGC的研究尚不明确,且尚无临床诊疗规范与共识。
Epstein-Barr virus-associated gastric carcinoma （EBVaGC） as a unique kind of gastric cancer that has been gradually recognized in recent years. It accounts for about 10% of all gastric cancers. In this review, we will focus on the relevant research on the epidemiology, histopathologic features, pathogenesis, treatment and prognosis of EBVaGC. The underlying mechanisms of EBVaGC has not been thoroughly elucidated, and there has been no consensus on the diagnosis and treatment of this unique form of gastric cancer. Therefore, further research is necessary to better understand the progression and treatment of EBVaGC.
出处
《世界华人消化杂志》
CAS
2017年第15期1375-1381,共7页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.81272693
中央高校基本科研业务费专项资金项目
No.2042016kf0087~~
