冷冻消融肝细胞癌患者发热原因分析及护理对策研究

Causes and nursing strategies of hepatocellular carcinoma patients with fever after cryo-ablation therapy

目的 探讨冷冻消融肝细胞癌（HCC）术后患者发热、感染的易感因素,并提出相应干预对策.方法 系统分析428例接受冷冻消融术HCC患者发热和感染情况,采用单因素分析和Logistic回归分析分析其影响因素,提出相应护理对策.结果 冷冻消融术后出现发热229例（53.5%）,并发感染6例（1.4%）;肿瘤大小、冷冻消融面积、Child-Pugh分级及术前白细胞水平是冷冻消融术后HCC患者发热的影响因素;冷冻消融面积、发热天数及冷冻消融前白细胞水平是冷冻消融术后HCC患者发生感染的影响因素.结论 应重视HCC患者冷冻消融术后发热、感染的易感因素,科学合理的护理是减少冷冻消融术后患者发热,减少感染发生的关键.

Objective To explore the susceptible factors of fever and infection among hepatocellular carcinoma （HCC） patients who received cryo-ablation （CA） therapy,and to propose intervention countermeasures accordingly.Methods The fever and infection status of totally 428 HCC patients who received CA therapy was examined systematically;then the influencing factors were analyzed by single factor analysis and logistic regression analysis;and finally,nursing strategies were proposed accordingly.Results Totally 229 patients developed fever （53.5%）,and 6 suffered from complicated infection （1.4%） after CA therapy;tumor size,CA area,Child-Pugh classification and preoperative leukocyte level were factors that contributed to the fever of HCC patients who received CA therapy.Conclusions We should attach importance to the susceptible factors of fever and infection among HCC patients who received CA therapy,and scientific intervention and nursing are the key to reducing the possibilities of fever and infection among patients who received CA therapy.