中西医药物联合心理干预治疗灼口综合征临床观察

Effect of combined therapy of traditional Chinese medicine and western medicine on burning mouth syndrome

目的探讨中西医药物联合心理干预对灼口综合征(BMS)的治疗效果。方法选取2012年9月至2014年9月江门市中心医院口腔科80例BMS患者,随机分为观察组和对照组,每组40例。观察组采用中西医药物联合心理干预治疗,对照组单纯采用中西医药物治疗,比较2组患者治疗效果。结果观察组显效27例,有效11例,无效2例,总有效率95.0%;对照组显效13例,有效4例,无效23例,总有效率42.5%。观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。2组患者治疗前临床症状无明显差异(P>0.05),治疗后观察组口舌烧灼疼痛、口舌麻木、烦躁失眠症状显著低于对照组(P<0.05)。治疗前2组汉密顿焦虑量及汉密顿抑郁无明显差异(P>0.05),治疗后观察组显著低于对照组(P<0.05)。结论中西医药物联合心理干预治疗BMS不仅可明显改善临床症状,且能改善患者生活质量,具有较好的临床疗效。

Objective To explore the therapeutic effect of combined therapy of traditional Chinese medicine and western medicine on burning mouth syndrome.Methods Eighty patients with burning mouth syndrome were randomly divided into observation group and control group,40 cases in each group.The observation group received traditional Chinese medicine and western medicine treatment combined with psychological therapy,while the control group was given traditional Chinese and western medicine treatment;two groups were compared before and after treatment.Results In observation group 27 cases were markedly effective,11 cases effective,2 cases invalid,total effective rate 95.0%;in control group it was markedly effective in 4 cases,effective 13 cases,invalid 23 cases,total effective rate 42.5%.The clinical effect of the observation group was significantly better than that of the control group （P 〈 0.05）.There were no significant differences in clinical symptoms in two groups before treatment （P 〉 0.05）;after treatment,tongue burning pain,numbness,irritability and insomnia symptoms of tongue in the observation group were significantly lower than those in the control group （P 〈 0.05）.There was no significant difference between the two groups of patients before treatment concerning the Hamilton Anxiety Rating and Hamilton Depression （P 〉 0.05）;after treatment,Hamilton Anxiety Rating and Hamilton depression of the observation group were significantly lower than the control group （P 〈 0.05）.Conclusion Combination of traditional Chinese medicine and western medicine therapy along with psychological intervention in the treatment of burning mouth syndrome not only improves the clinical symptoms,but also can improve the quality of life of patients with good clinical efficacy.