薄芝糖肽联合神经节苷脂在高危儿早期干预中的疗效观察

Investigation of the earlier curative effects of Bozhi glycopeptides associated with gangloisideon high risk infants

目的探究薄芝糖肽联合神经节苷脂在高危儿早期干预中的临床效果。方法将134例患儿按随机数字法分为对照组和观察组,每组67例,对照组进行常规治疗辅以神经节苷脂,观察组在对照组的基础上加用薄芝糖肽,治疗结束后观察患者的治疗效果。结果观察组明显提高了患儿的显效率及治疗总有效率,显著降低治疗无效率,血清免疫球蛋白水平(IgA,Ig G,IgM,C_3)及T淋巴细胞亚群水平(CD3^+,CD4^+,CD4^+/CD8^+)明显改善,与对照组差异显著具有统计学意义(P<0.05)。结论薄芝糖肽联合神经节苷脂可有效促进患儿受损脑功能恢复,值得深入研究并推广应用。

Objective ：To observe the effects of Bozhi glycopeptide and gangloiside on high risk infants. Methods： 134 high risk infants were randomly divided into the observation group and the control group, and every group had 67 patients. The control group was given conventional and gangloiside treating, and the observation group was also given Bozhi glycopeptides besides conventional and gangloiside treating. Clinical efficacy of the two groups were compared after treatment. Results ： In the observation group, the therapeutic effects and the levels of immunoglobulins （ IgA, IgG, IgM, Cs ） and T cell subsets （ CD3 ＋ , CD4＋ , CD4＋ / CD8 ＋ ） were better than control group （ P 〈 0.05 ） after treatment. Conclusion ： Combine Bozhi glycopeptides with gangloiside improves children＇s impaired brain function recovery, which is worthy of promotion.