阿托伐他汀钙与西洛他唑联用对糖尿病周围血管病变的治疗评价

Evaluation on Atorvastatin Calcium and Cilostazol in Treatment of Diabetic Peripheral Vasculopathy

目的评价阿托伐他汀钙与西洛他唑联用对糖尿病周围血管病变临床治疗效果。方法资料选取2015年12月—2016年12月该院收治的54例糖尿病周围血管病变患者,对其病历进行详细的回顾与分析,将其分为观察组和对照组,每组患者各为27例,给予对照组患者实施常规治疗,而给予观察组患者则阿托伐他汀钙与西洛他唑联合使用,分别观察两组患者采用不同治疗方法后临床治疗效果和用药后的不良反应。结果统计发现观察组患者临床治疗总有效率为96.30%,而对照组为70.37%,相比观察组明显高于对照组,差异有统计学意义(P<0.05)。而对比两组患者用药后不良反应发生率发现,观察组为7.41%,对照组为11.11%,相比差异无统计学意义(P>0.05)。结论对于糖尿病周围血管病变患者采用阿托伐他汀钙联合西洛他唑药物可大幅度提高患者临床治疗总有效率,且无明显不良反应,得到患者和家属的一致好评。

Objective To evaluate the effect of atorvastatin calcium and cilostazol in treatment of diabetic peripheral vasculopathy. Methods 54 cases of patients with diabetic peripheral vasculopathy admitted and treated in our hospital from December 2015 to December 2016 were selected and divided into two groups with 27 cases in each, the control group adopted the routine treatment, while the observation group adopted the atorvastatin calcium and cilostazol, and the clinical treatment effect and adverse reactions after medication were observed. Results The total clinical treatment effective rate in the observation group was obviously higher than that in the control group（96.3% vs 70.37%）, and the difference was statistically significant（P〈0.05）, and the difference in the incidence rate of adverse reactions after medication between the observation group and the control group was not statistically significant （7.41% vs 11.11%）（P〉0.05）. Conclusion The atorvastatin calcium and cilostazol in treatment of diabetic peripheral vasculopathy can greatly improve the total clinical treatment effective rate without obvious adverse reacctions, which is well reviewed by patients and their family.