摘要
目的研究在结直肠癌合并2型糖尿病采取CapeOx与二甲双胍联合治疗的临床效果以及价值。方法选取该院自2013年12月—2016年12月期间收治的36例结直肠癌合并2型糖尿病患者,采取计算机表法随机均分成参照组(n=18)与实验组(n=18),将采取CapeOx方案单独治疗患者作为参照组,将采取CapeOx与二甲双胍联合治疗患者作为实验组,分析对比两组患者经不同方案治疗之后的治疗不良反应、临床治疗效果等变化情况。结果实验组患者经对症方案治疗之后治疗不良反应5.55%、临床治疗效果94.44%等指标与参照组患者治疗不良反应38.88%、临床治疗效果66.67%进行对比数据差异有统计学意义(P<0.05)。结论将CapeOx与二甲双胍联合治疗应用在结直肠癌合并2型糖尿病患者中疗效相对显著,可以显著降低患者不良反应,提升临床治疗总有效率,改善患者日后生活质量,值得广泛应用。
Objective To research the clinical effect and value of metformin and CapeOx plan in treatment of colorectal cancer and type 2 diabetes. Methods 36 cases of patients with colorectal cancer and type 2 diabetes admitted and treated in our hospital from December 2013 to December 2016 were selected and randomly divided into two groups with 18 cases in each, the control group adopted the simple CapeOx plan, while the experimental group adopted the metformin and CapeOx plan, and the treatment adverse reactions and changes of clinical treatment effect were compared between the two groups after treatment. Results After treatment, the differences in the incidence rate of adverse reactions and clinical treatment effect between the experimental group and the control group were obvious with statistical significance （5.55%, 94.44% vs 38.88%, 66.67%）（P〈0.05）. Conclusion The curative effect of metformin and CapeOx plan in treatment of colorectal cancer and type 2 diabetes is obvious, which can obviously reduce the adverse reactions of patients, improve the total clini- cal treatment effective rate and improve the quality of life, and it is worth wide application.
出处
《糖尿病新世界》
2017年第6期70-71,共2页
Diabetes New World Magazine
