白花蛇舌草多糖研究进展

Research progress of polysaccharides from Hedyotis diffusa Willd.

多糖为白花蛇舌草重要活性成分之一,主要是由鼠李糖、葡萄糖、半乳糖、阿拉伯糖及甘露糖组成的杂多糖;不同产地、不同采收季节对多糖含量具有一定影响;主要的提取方法是通过不同的提取温度、时间等条件,用各种柱层析得到多糖纯品;主要用苯酚-硫酸法、红外光谱及气相色谱分析法测定含量。白花蛇舌草多糖具有抗氧化、免疫调节、抗肿瘤等生物活性,其作用机制与提高免疫力、清除自由基作用有关。

Polysaccharide from Hedyotis diffusa Willd. is main biological active component which contain main residues of rhamnose, glucose, galactose, arabinose, and mannose, the polysaccharide content is different from different habitat and harvest season. The polysaccharide was extracted with different temperature and time, and purified by various column chromatography. The content of polysaccharide was determined according to phenol-sulfuric acid, IR and GC methods. The biological activities of antioxidant, anticancer, and immunoregulation of the polysaccharide may depend on improving immunity and scavenging free radical.