起搏器植入后升级为CRT的临床研究

The clinical study of CRT upgrading after pacemaker Implantation

目的研究植入传统起搏器后升级到心脏再同步治疗(CRT)的入选条件升级时机、临床疗效等相关问题。方法选择已植入起搏器患者,根据心脏左室舒张末期内径(LVDd)增大情况,心衰程度,电池电量等因素,适时升级到CRT,并比较升级前后LVDd大小,心脏射血分数(EF)变化的差异。结果升级CRT后LVDd减小,t=3.78,p<0.01。EF升高,t=8.89,p<0.01。与升级前比较均有显著性差异。结论对于起搏器依赖患者伴有心脏LVDd扩大、心功能减退均应及时升级到CRT,有利改善心功能。

Objective To study the admission,opportunity,clinical effect and other relative problems of the Upgrade to CRT （cardiac resynchronization therapy） after conventional pacemaker Implantation.Methods We upgraded the patients who underwent pacemaker Implantation to CRT according to LVDd （left ventricular end-diastolic diameter）,EF （ejection fraction） and battery level,and then compare the LVDd and EF before and after the upgrade.Results Both the decrease of LVDd （t =3.78,p〈0.01） and the increase of EF （t=8.89,p〈0.01） after the upgrade had statistical significance.Conclusions Upgrading to CRT in time is a effctive way for Pacemaker-dependent patients with LVDd increase and heart dysfunction to improve cardiac function.